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Can You Use Retinol With Vitamin C?

Separate or space out

With care.

L-ascorbic acid needs a pH around 3.5 while retinol converts best near neutral. Layered together each destabilizes the other, and the low pH increases retinoid stinging.

How to use Retinol and Vitamin C

Vitamin C in the morning under sunscreen, retinol at night. This is the standard split and it costs you nothing in efficacy.

General guidance from common dermatological advice, not medical advice. If you use a prescription treatment, follow your prescriber’s instructions.