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Can You Use Retinol With Benzoyl Peroxide?

Do not combine

Not in the same routine.

Benzoyl peroxide is an oxidizer that chemically degrades retinol on contact, so you get the irritation of both with the benefit of neither.

How to use Retinol and Benzoyl Peroxide

Benzoyl peroxide in the morning, retinol at night. Adapalene is the exception; it is stable against benzoyl peroxide and the two are co-formulated in some prescriptions.

General guidance from common dermatological advice, not medical advice. If you use a prescription treatment, follow your prescriber’s instructions.