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Can You Use Niacinamide With Retinol?

Works well together

Yes.

Niacinamide measurably reduces retinoid irritation by supporting ceramide synthesis. Many retinol products now include it for exactly this reason.

How to use Niacinamide and Retinol

Layer niacinamide first, then retinol. This is an actively good combination.

General guidance from common dermatological advice, not medical advice. If you use a prescription treatment, follow your prescriber’s instructions.