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Can You Use Azelaic Acid With Retinol?

Separate or space out

With care.

Azelaic acid is well tolerated and often paired with retinoids, but both increase surface sensitivity during the first few weeks of use.

How to use Azelaic Acid and Retinol

Introduce one at a time. Once both are established, layer azelaic acid first and retinol second, or alternate nights.

General guidance from common dermatological advice, not medical advice. If you use a prescription treatment, follow your prescriber’s instructions.