
No.5+ Glutathione TXA Advanced Dark Spot Ampoule Concentrate
Serum · 10.7 g
Where to buy
Stylevana
10.7 g
30%$16.80$24.00Buy at StylevanaYesStyle
10.7 g
30%$16.80$24.00Buy at YesStyle
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Key ingredients
Found in the full ingredient list below. Check how it layers with your routine
Made for
Full ingredients (24)
- Hippophae Rhamnoides Water
- Tranexamic Acid
- Tripropylene Glycol
- Glutathione
- Niacinamide
- 1,2-Hexanediol
- Diethoxyethyl Succinate
- Hydroxyacetophenone
- Hydroxyethylcellulose
- Ethylhexylglycerin
- Disodium EDTA
- Ascorbic Acid
- Bisabolol
- Panthenol
- Tocopherol
- Thioctic Acid
- Glycerin
- Water
- Cyanocobalamin
- Butylene Glycol
- Caprylic/Capric Triglyceride
- Polyglyceryl-3 Methylglucose Distearate
- Ubiquinone
- Glutathione (100%)
Listed from highest to lowest concentration. Formulas change, so check the packaging if you avoid an ingredient.
Product details

2-week dark spot ampoule
Pure glutathione powder and a tranexamic acid ampoule, mixed fresh at first use for targeted dark spot care.
Numbuzin’s No.5 Ampoule is the intensive partner to its daily No.5+ serum. The cap holds pure glutathione powder; press it and it drops into a vitamin ampoule of sea buckthorn water, tranexamic acid and more glutathione, so the actives stay fresh until the day you start. One bottle is a two-week course for dull tone and stubborn dark spots.
- Sea buckthorn water, the vitamin tree
- #1
- Sea buckthorn water, the vitamin tree
- Tranexamic acid’s place on the list
- #2
- Tranexamic acid’s place on the list
- One bottle, once mixed
- 2 weeks
- One bottle, once mixed

What’s inside
The ingredients doing the work
Glutathione
Pure glutathione powder sits in the cap, and more glutathione is in the ampoule itself. A brightening antioxidant that helps balance tone and fade the look of dark spots.
No. 4, 24 of 24 on the list
Tranexamic acid
Second on the list, it targets dark spots, uneven tone and lingering marks.
No. 2 of 24 on the list
Vitamin tree water
Sea buckthorn water replaces plain water as the base of the ampoule.
No. 1 of 24 on the list
Niacinamide + vitamins
Niacinamide and vitamin C brighten, while panthenol and vitamin B12 help keep skin comfortable.
No. 5, 12, 14, 19 of 24 on the list
Antioxidants + bisabolol
Vitamin E, alpha-lipoic acid and coenzyme Q10 back up the glutathione, with soothing bisabolol.
No. 13, 15, 16, 23 of 24 on the list

How to use
Press, shake, apply
- 1
Press
Press the yellow cap down firmly to release the glutathione powder into the ampoule.
- 2
Shake
Shake well for about 20 seconds until the powder is fully mixed.
- 3
Attach
Remove the yellow cap and fit the applicator.
- 4
Apply
After toner, apply a few drops over dark spots or the whole face, then moisturize, with sunscreen by day.

Two weeks to a brighter tone
A fresh-mixed course of glutathione and tranexamic acid for the dark spots that won’t budge.
Good to know
- Use within two weeks of mixing, and store it away from direct sunlight to keep it from oxidizing.
- Glutathione has a strong, pungent smell; Numbuzin says that’s normal.
- Skin irritation tested, but Numbuzin suggests mixing it with your other products at first and patch testing if your skin is sensitive. Once skin adapts, use it on its own.
- Brightening care: wear sunscreen during the day while you use it.
- For stubborn spots, Numbuzin suggests layering it over the No.5+ Glutathione Vitamin Concentrated Serum.
- Sold as a single 10.7 g vial.
